Prohormone & Supplement Ingredients:


Resveratrol is a stilbenoid, a type of polyphenol, and a phytoalexin produced naturally by several plants when under attack by pathogens such as bacteria or fungi.

Resveratrol is currently a topic of numerous studies. In mouse and rat experiments, anti-cancer, anti-inflammatory, blood-sugar-lowering and other beneficial cardiovascular effects of resveratrol have been reported. Most of these results have yet to be replicated in humans. Despite mainstream press alleging resveratrol's anti-aging effects, there is little scientific basis for these claims.

Resveratrol is found in the skin of red grapes and is a constituent of red wine. Resveratrol has also been produced by chemical synthesis or by biotechnological synthesis (metabolic engineered microorganisms) and is sold as a nutritional supplement derived primarily from Japanese knotweed.

A compound that binds to estrogen receptors and elicits similar responses to endogenous estrogens is considered an estrogen agonist, while a compound that binds estrogen receptors but prevents or inhibits the response elicited by endogenous estrogens is considered an estrogen antagonist. The chemical structure of resveratrol is very similar to that of the synthetic estrogen agonist, diethylstilbestrol, suggesting that resveratrol might also function as an estrogen agonist. However, in cell culture experiments resveratrol acts as an estrogen agonist under some conditions and an estrogen antagonist under other conditions. In estrogen receptor-positive breast cancer cells, resveratrol acted as an estrogen agonist in the absence of the endogenous estrogen, 17beta-estradiol, but acted as an estrogen antagonist in the presence of 17beta-estradiol.

At present, it appears that resveratrol has the potential to act as an estrogen agonist or antagonist depending on such factors as cell type, estrogen receptor isoform (ER alpha or ER beta), and the presence of endogenous estrogens.
Supplements with this ingredient:
Advanced Post Cycle Therapy (Post Cycle Support)
Forged: ATD (Test Boosters/Hormone Regulation)
Natural PCT (Post Cycle Support)

Links to additional information on Resveratrol
Resveratrol (Added on 12/30/2010)
Resveratrol: A molecule whose time has come? And gone? (Added on 4/25/2011)
Amelioration of oxidative stress by antioxidants and resveratrol in PC12 cells (Added on 4/25/2011)
Resveratrol improves health and survival of mice on a high-calorie diet (Added on 4/25/2011)
Is Resveratrol a Performance Enhancing Drug? (Added on 3/18/2013 1:11:00 PM)

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