Prohormone & Supplement Ingredients:

Glabra (Licorice)

Glabra is a renaming of Glycyrrhiza Glabra, which is aka Licorice. That's right, Licorice. As far as supplements go, Licorice does have some effects.

Licorice is a mild laxative. Large doses of glycyrrhizinic acid and glycyrrhetinic acid in liquorice extract can lead to hypokalemia and increases in blood pressure, a syndrome known as apparent mineralocorticoid excess.

These side effects stem from the inhibition of the enzyme 11?-hydroxysteroid dehydrogenase (type 2) and subsequent increase in activity of cortisol on the kidney. 11?-hydroxysteroid dehydrogenase normally inactivates cortisol in the kidney; thus, licorice's inactivation of this enzyme makes the concentration of cortisol appear to increase.

Cortisol acts at the same receptor as the hormone aldosterone in the kidney; thus, the effects mimic aldosterone excess, although aldosterone remains low or normal during licorice overdose. Cortisol does not actually increase either; however, its activity in the kidney effectively increases due to the disabling of this enzyme.

To decrease the chances of these serious side effects, deglycyrrhizinated licorice (DGL) preparations are available.

Licorice cam affect the body's endocrine system. It can lower the amount of serum testosterone, but whether it affects the amount of free testosterone is unclear.

So, Licorice decrease testosterone, increases blood pressure may increase catabolic hormones, and it's a laxative. If any of that iswhat you're looking for, have at it.
Supplements with this ingredient:
None (for now)

Links to additional information on Glabra (Licorice)

No Informational URLS have been entered!
only members can suggest new info links