Prohormone & Supplement Ingredients:

1-Androstenediol (1-AD)

Synonyms: 5alpha-androst-1-en-3,17-diol, 1-AD

1-Androstenediol (1-AD) is an anabolic pro-steroid structurally related (but not identical) to 5-androstenediol. It is one of the many byproducts of the body's normal processing of steroid hormones. In the body 1-AD is converted into 1-Testosterone.

1-AD was discovered in the 1940s and a metabolic study was published in 1972. Aside from these studies, 1-AD received little attention until recently.

In the 1990s governments worldwide tried to eliminate access to anabolic steroids, thereby creating not only a thriving black market, but a strong incentive to find alternative muscle-building enhancers. This led to the rediscovery of 1-AD and 1-Testosterone by chemist Patrick Arnold compounds that (in some countries, at least) were not covered by existing anti-steroid laws.

The known facts about 1-Androstenediol:

It is an orally active, naturally occurring prohormone.

Oral bioavailability appears to be higher than most anabolic prohormones, but has not yet been measured quantitatively.

Does not convert to estrogens in the body hence, won't cause breast enlargement or estrogen-related water retention.

Conversion to DHT is low or zero. Therefore, 1-AD is not likely to cause acne, scalp hair loss, or body/facial hair growth.

The liver converts 1-AD to 1-Testosterone, which is a very potent anabolic steroid. This conversion could be called "activation", but 1-AD also has anabolic action of its own. The figure of 154% refers to this action. The inactivation of both 1-AD and 1-Testosterone, prior to their elimination from the body, also takes place in the liver, so claim 9 is not entirely accurate.

1-AD is non-toxic with short-term use long-term studies have not been done.

1-AD, both on its own and through its metabolite 1-Testosterone, increases muscle mass and strength without causing significant water retention in the muscles. In this sense it "hardens muscles".

In the absence of long-term studies, we have only short-term studies and anecdotal reports to go on, and these support none of the negative claims.
Supplements with this ingredient:
None (for now)

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