ZMA Information (Test Boosters/Hormone Regulation)

ZMA by

Manufactured by:
iForce Nutrition

Serving Size: 3 Capsules
Serving Per Container: 30

Amount Per Serving:
Vitamin B6 10.5 mg
Magnesium 450 mg
Zinc 30 mg

Suggested Use:
Take 3 capsules daily, within 30-60 minutes before bedtime, preferably on an empty stomach. To increase the absorption and effects of ZMA, avoid eating dairy or other calcium containing foods before taking your dose of ZMA.

You see ZMA touted al over the palce as a test booster. Well, I've done the research (link below) and I remain unconvinced. If you're low on zin or magnesium, take it, but if you're looking to test boost, I think there's better stuff out there.

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Magnesium Aspartate (Magnesium)

Magnesium aspartate is the magnesium salt of aspartic acid and is used as a a mineral supplement for magnesium supplementation.

Magnesium is a vital component of a healthy human diet. Human magnesium deficiency is relatively common, with only 32% of the United States meeting the RDA-DRI. Low levels of magnesium in the body has been associated with the development of a number of human illnesses such as asthma, diabetes, and osteoporosis.

Intracellular magnesium is correlated with intracellular potassium. Magnesium is absorbed in the gastrointestinal tract, with more absorbed when status is lower. In humans, magnesium appears to facilitate calcium absorption. Low and high protein intake inhibit magnesium absorption, and other factors such as phosphate, phytate, and fat affect absorption.

Spices, nuts, cereals, coffee, cocoa, tea, and vegetables are rich sources of magnesium. Green leafy vegetables such as spinach are also rich in magnesium as they contain chlorophyll. Observations of reduced dietary magnesium intake in modern Western countries compared to earlier generations may be related to food refining and modern fertilizers that contain no magnesium.

Numerous magnesium dietary supplements are available. Magnesium oxide, one of the most common because it has high magnesium content per weight, has been reported to be the least bioavailable. Magnesium citrate has been reported as more bioavailable than oxide or amino-acid chelate forms.

Excess magnesium in the blood is filtered at the kidneys, and for this reason it is difficult to overdose on magnesium from dietary sources alone. With supplements, overdose is possible, however, particularly in people with poor renal function.

Alcoholism can produce a magnesium deficiency, which is easily reversed by oral or parenteral administration, depending on the degree of deficiency.

Vitamin B-6

The primary role of vitamin B6 is to act as a coenzyme to many other enzymes in the body that are involved predominantly in metabolism. This role is performed by the active form, pyridoxal phosphate. This active form is converted from the two other natural forms founds in food: pyridoxal, pyridoxine and pyridoxamine.

Vitamin B6 is involved in the following metabolic processes:

amino acid, glucose and lipid metabolism

neurotransmitter synthesis

histamine synthesis

hemoglobin synthesis and function

gene expression

Amino acid metabolism

Pyridoxal phosphate is involved in almost all amino acid metabolism, from synthesis to breakdown.

Neurotransmitter synthesis

Pyridoxal phosphate-dependent enzymes play a role in the biosynthesis of four important neurotransmitters: serotonin, epinephrine, norepinephrine and gamma-aminobutyric acid. Serine racemase, which synthesizes the neuromodulator D-serine, is also a pyridoxal phosphate-dependent enzyme.

Histamine synthesis

Pyridoxal phosphate is involved in the metabolism of histamine.

Hemoglobin synthesis and function

Pyridoxal phosphate aids in the synthesis of heme and can also bind to two sites on hemoglobin to enhance the oxygen binding of hemoglobin.

Gene expression

It transforms homocysteine into cistation then into cysteine. Pyridoxal phosphate has been implicated in increasing or decreasing the expression of certain genes. Increased intracellular levels of the vitamin will lead to a decrease in the transcription of glucocorticoid hormones. Also, vitamin B6 deficiency will lead to the increased expression of albumin mRNA. Also, pyridoxal phosphate will influence gene expression of glycoprotein IIb by interacting with various transcription factors. The result is inhibition of platelet aggregation.

Zinc Aspartate

Zinc L-aspartate, often simply called zinc aspartate, is a chelated mineral supplement and an important naturally occurring bioavailable delivery form of zinc. Zinc aspartate is a salt of zinc with the amino acid aspartic acid.

Zinc is an essential trace element, necessary for plants, animals, and microorganisms. Zinc is found in nearly 100 specific enzymes (other sources say 300), serves as structural ions in transcription factors and is stored and transferred in metallothioneins. It is "typically the second most abundant transition metal in organisms" after iron and it is the only metal which appears in all enzyme classes.

In humans, zinc interacts with "a wide range of organic ligands" and has roles in the metabolism of RNA and DNA, signal transduction, and gene expression. It also regulates apoptosis.