RA Silver Bullet PCT System Information (Post Cycle Support)

RA Silver Bullet PCT System by


Ratings
Ingredients
Manufactured by:
RA Anabolic Technology

Serving Size: 1 Capsule
Servings Per Container: 60

Other Ingredients: Maltodextrin, Magnesium Sterate, Gelatin, Titanium Dioxide, FD&C Yellow #5.

Designed to be taken immediately following the pro hormone cycle RA Anabolic Stack, the Silver Bullet PCT System works to cleanse the liver, support healthy testosterone, and suppress estrogen levels.

This is a very balanced, and effective product for the money. It also works to balance and promote healthy blood flow, and boost the immune system.

We don't see too many products with the compound Daidzein, however, this anti-estrogen compound seems to be very promising.

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Acacetin (5,7-Dihydroxy-4-methoxyflavone)

Acacetin is an anti-aromatase and estrogenic activity blocker that is derived from the Damiana Plant. Aromotase is the essential part to estrogen synthesis in the human body and Acacetin has been shown by researchers to be the most effective natural substance to block the synthesis.

Acacetin is used by body builders, athletes and weightlifters to control the amount of estrogen in their bodies when cycling with androgenic compounds to avoid complications due to a conflicting hormonal balance. It is also being considered as a relief agent for women with menopausal symptoms and as a preventative measure for women at risk for, but without developed hormone sensitive cancers of the breast, uterus and ovaries.

What Acacetin is used for:


Weight loss
Relief from menopause symptoms
Tumor growth prevention
Reduction of Estrogen synthesis

Acacetin is an effective weight loss measure has it blocks the estrogen synthesis in the body and forces the body to seek contractile protein from the synthesis of estrogen receptor fat cells. It acts upon the body through a natural suppression process but will not eliminate or permanently disrupt the ability to synthesize aromatase or estrogen. Upon cessation of the cycling routine, the body?s natural aromatase and estrogen activity will return to normal amounts. Acacetin is not a banned substance by most sporting bodies.

In one research study, Acacetin lowered aromatase synthesis by over 60%. There is no supported dosage amount for Acacetin however it is recommended that it is taken in as controlled a quality format as possible. Women who are pregnant or breastfeeding should not take Acacetin as it may interfere with the sex hormone development process of the fetus. Anyone with a diagnoses hormone sensitive cancer should avoid taking the supplement as well.

Daidzein (4,7-Dihydroxyisoflavone)

Daidzein is derived from numerous plant source including kudzu. It is an estrogen and anti estrogen agent that works on binding with estrogen receptor cells in the body. It has been shown to be effective in relieving hot flashes in menopausal women and may play an important role in preventing the development of tumors associated with hormone sensitive cancers.

Daidzein is most often taken in a supplement for and can come as an all-natural or natural soy isoflavone. The daily recommended dosage is 34mgs twice a day in combination with Genistein to increase the colon absorption of the isoflavones.

Uses for Daidzein (4,7-Dihydroxyisoflavone)
  • Preventative for breast cancer
  • Control hormone related hair growth
  • Relive menopausal symptoms
There is also indication that Daidzein has a positive anti-oxidant influence on cells and may be an important part of maintaining cell resiliency and structure. Data is inconclusive as to how great the anti-oxidant effect is on the body with Daidzein being the primary source of the anti-oxidant. It is a primary source of the positive Isaflavones that are typically deficient in the Western diet.

It is very important to note that evidence is suggesting a positive prevention aspect for hormone related breast cancers in women because of the estrogen and anti estrogen properties of Daidzein. It is recommended as a preventative supplement for women who have not shown any development of cancerous or pre-cancerous cells related to hormone sensitive cancers.

Daidzein should not be taken by women who are pregnant, breastfeeding or who have hormone sensitive cancers such as certain types of breast and ovarian cancers. Studies indicate that the estrogen and anti-estrogen properties of Daidzein can stimulate tumor growth in estrogen receptor cancer cells.

Diindolylmethane (DIM)

Diindolylmethane (DIM) is a stable indole found in cruciferous vegetables which promotes a beneficial estrogen metabolism in both women and men. There are also indication that is possesses anti-cancer properties, and as well as being an anti-viral.

The National Cancer Institute of the United States has begun clinical trials of DIM to look at its anti-cancer properties. DIM is also being looked at as treatment for viral infections and antibiotic resistant bacteria.

DIM is currently used to treat Recurring Respiratory Papillomatosis, a rare respiratory disease with tumors in the upper respiratory tracts caused by the human papilloma virus. DIM is also in Phase III clinical trials for cervical dysplasia, a pre-cancerous condition also caused by the human papilloma virus. Similarly, it has been studied and shown promising results as a immunostimulant against HPV.

As a dimer of indole-3-carbinol, diindolylmethane promotes beneficial estrogen metabolism in both genders by reducing 16-hydroxy estrogen metabolites and increasing the formation of 2-hydroxy estrogen metabolites.

There are claims that Diindolylmethane is the most active cruciferous substance for promoting beneficial estrogen metabolism in women and men. DIM is formed from its precursor indole, Indole-3-carbinol (I3C), after the enzymatic release of I3C from parent glucosinolates. Early experiments demonstrated animal diets with added DIM prevented chemically induced cancer.

Pure DIM was first used in 1987 as a dietary supplement in animals, was shown to be non-toxic, and to be a breast cancer preventative. The mechanisms by which DIM prevents cancer in animals has subsequently been shown to involve a reduction in activity of the estrogen receptor system, promotion of beneficial estrogen metabolism, and support for selective apoptosis, or "programmed cell death" which removes damaged cells.

Supplemental use of DIM in humans is effective in adjusting the pathways of estrogen metabolism to favor the production of 2-hydroxy estrogen metabolites. These shifts in estrogen metabolites were significant and showed an approximate 75% increase in production of 2-hydroxyestrone and a 50% decrease in 16-hydroxyestrone. An increased proportion of 2-hydroxy metabolites is correlated to protection from breast cancer. Case-control studies have documented that low levels of 2-hydroxy metabolites are associated with various types of cancers in both menand women.

DIM is unique among all phytonutritionals with regard to its ability to favorably modify estrogen metabolism in the direction of greater 2-hydroxy estrogen production.

So I found research that claim DIM is an:

aromatase inhibitor
anti-estrogen
estrogen convertor

Which one is it really? I'm afraid I'm not sure.

Grape Seed Extract

Grape seed extracts are derivatives from whole grape seeds that have a concentration of vitamin E, flavonoids, linoleic acid, and OPCs.

Preliminary studies in humans and animals show grape seed extract may be useful to treat high blood pressure and high cholesterol. By limiting lipid oxidation, phenolics in grape seeds may reduce risk of heart disease, such as by inhibiting platelet aggregation and reducing inflammation. A polyphenol contained in grape seeds is resveratrol which may interfere with cancer cell growth and proliferation, as well as induce apoptosis, among a variety of potential preventive effects.

Currently, there are clinical trials underway to assess the effect of grape seed extracts on human breast cancer, blood estrogen levels in postmenopausal women, and coronary artery disease.

Of note to strength athletes, grape seed extract is also an aromatase inhibitor; it suppresses the conversion of testosterone to estradiol.

Milk Thistle (SILYMARIN)

The milk thistle is a thistle of the genus Silybum Adans., a flowering plant of the daisy family (Asteraceae). They are native to the Mediterranean regions of Europe, North Africa and the Middle East. The name "milk thistle" derives from two features of the leaves: they are mottled with splashes of white and they contain a milky sap.

The seeds of the milk thistle have been used for 2000 years to treat chronic liver disease and protect the liver against toxins. Increasing research is being undertaken on the physiological effects, therapeutic properties and possible medical uses of milk thistle.

Research into the biological activity of silymarin and its possible medical uses has been conducted in many countries since the 1970s. Milk thistle has been reported to have protective effects on the liver and to greatly improve its function. It is typically used to treat liver cirrhosis, chronic hepatitis (liver inflammation), toxin-induced liver damage, and gallbladder disorders.

Reviews of the literature covering clinical studies of silymarin vary. A review using only studies with both double-blind and placebo protocols concluded that milk thistle and its derivatives "does not seem to significantly influence the course of patients with alcoholic and/or hepatitis B or C liver diseases".

A different review of the literature performed for the U. S. Department of Health and Human Services found that while there is strong evidence of legitimate medical benefits, the studies done to date are of uneven design and quality that no firm conclusions about degrees of effectiveness for specific conditions or appropriate dosage can yet be made.

A review of studies of silymarin and liver disease which are available on the web shows an interesting pattern in that studies which tested low dosages of silymarin concluded that silymarin was ineffective[13], while studies which used significantly larger doses concluded that silymarin was biologically active and had therapeutic effects.

Beside benefits for liver disease, other unproven treatment claims include:

Used as a post (oral steroid) cycle therapy for body builders and/or in the hopes of reducing or eliminating liver damage

Lowering cholesterol levels

Reducing insulin resistance in people with type 2 diabetes who also have cirrhosis

Reducing the growth of cancer cells in breast, cervical, and prostate cancers.

Used in many products claiming to reduce the effects of a hangover

Used by individuals withdrawing from opiates, especially during the Acute Withdrawal Stage.

Reducing liver damaging effects of chemotherapeutic drugs

Clinical study has shown that liver function tests can be improved in active hepatitis patients.

Piperine

Piperine is the alkaloid responsible for the pungency of black pepper and long pepper, along with chavicine (an isomer of piperine). It has also been used in some forms of traditional medicine and as an insecticide.

Piperine has been found to inhibit human CYP3A4 and P-glycoprotein, enzymes important for the metabolism and transport of xenobiotics and metabolites. In animal studies, piperine also inhibited other enzymes important in drug metabolism. By inhibiting drug metabolism, piperine may increase the bioavailability of various compounds and alter the effectiveness of some medications.

Piperine may also have some harmful side effects. Preliminary evidence shows it may be toxic in some circumstances, and may even interfere with reproductive processes, including negative effects on sperm. Piperine at doses higher than 15 mg daily may affect the metabolism of a wide range of drugs. Even lower doses may affect the bodys metabolism of some drugs.

Piperine may also form cancer-causing substances when eaten with nitrates. Experts suggest that people who take piperine supplements should be careful when also eating food that contains nitrates as a preservative.

Not enough human studies have been done to determine the side effects of chronic supplementation with piperine. For the time being, it is a good idea to take 2 days off a week, and one full week off each month from the use of a piperine supplement. It is quite likely that the small amounts of piperine could provide health benefits while larger amounts could be toxic or damaging to the liver or other organs.

White Button Mushroom (Agaricus bisporus)

The White Button Mushroom is common to North America and is available in many different forms from the natural mushroom form used in cooking, to dried forms, tea and as a supplement. The White Button Mushroom is traditionally valued as a source of nutrients for boosting the immune system and helping to fight off respiratory and viral infections. Recent clinical studies have shown positive results in its role as a preventative aid for hormone-sensitive breast cancers and other breast cancers. There is also evidence that it contains a high amount of Vitamin D which can benefit people with deficiencies.

Uses for White Button Mushroom (Agaricus bisporus)
  • Boost immune system
  • Manage blood sugar
  • Preventive for hormone-sensitive cancers
  • Colds and Flu
  • Osteoporosis
  • Arthritis
What the White Button Mushroom has:
  • Sodium
  • Vitamin D
  • potassium
  • phosphorus
  • conjugated linoleic acid
  • antioxidants
  • Protocatechuic acid
  • Pyrocatechol
The high levels of potassium, sodium and vitamin D suggest that the White Button Mushroom can be an effective aid in the management of cholesterol and blood sugar levels. It is the recent work done on studying the impact of the Protocatechuic acid and Pyrocatechol contained in the mushroom which is showing positive preventative effects on hormone sensitive cancers. Currently, there is no preference for the body utilizing this aspect of the White Button Mushroom but the high medical dosage amount suggests that it is more realistic to be consumed as a supplement.

There are no known counter indications for consuming White Button Mushroom as a food or supplement, however some people may have sensitivity to the White Button Mushroom in its natural form or be allergic to it in all forms. Before taking White Button Mushroom in a large dosage amount, consult your doctor if you have known allergies or try a small amount first.