Finaflex 550-XD Information (Prohormones)

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Manufactured by:
Redefine Nutrition

Serving Size: 1 Capsule
Servings Per Container: 60

What's in it?

Vitamin C (as Ascorbic Acid) 50mg

Their "Proprietary Blend"
Finaflex 550-XD 170mg - this consists of 3b-enanthoxy-19-nor-androst-4-ene-17-one, Bergamottin, Naringin, and Arimistane (Androsta-3,5-diene-7,17-dione)

There's Liver Detox stuff tossed in as well: N-Acetyl L-Cysteine, Milk Thistle Extract (4:1)(seed)

And a bunch of other junk: Maltodextrin, gelatin, silica, magnesium Stearate, titanium dioxide, FD&C Blue #1, FD&C Red #40, FD&C Yellow #6.

Hmmm....

I waffled a bit here on whether or not to include this as a prohormone or a "test booster" and decided to go with Prohormoned. I'm not sure I'm convinced though. There's definitely some users out there gaining size and strength on 19-nor compounds (which is what this contains). The actual compound here is pretty new though, adn I think the jury is still out.

What I certainly don't like here and their "propriety blend".

As far as prohormones go, the only one we have here is 3b-enanthoxy-19-nor-androst-4-ene-17-one and guess what? We have no idea how much there is, since it's simply listed as part of their "blend" along with other things the aren't prohormones.

What this means here is when you take it, you have no idea, NO IDEA, how much 3b-enanthoxy-19-nor-androst-4-ene-17-one you're getting in a serving. 169mg? Or 1mg?

Now I'm being a bit dickish here, but you get the idea. As a user, I what to know how much I'm getting.

And another thing.... I understand how marketing works. Ohhhh, look at the pretty pills! But when it comes to performance enhancing supplements, what do compnaies put stuff like FOOD DYES in them.

Give me the goods, tell me how much I'm getting(!), and don't worry about making them pretty, mmmmkay?

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3b-enanthoxy-19-nor-androst-4-ene-17-one (Decasterone)

With so many different compounds out there, and some many different ways suplpement compnaies write then, and so many fly-by-night companies that don't have the integrity they should, who's to know what's "real" and what's not?

3b-enanthoxy-19-nor-androst-4-ene-17-one is also called Decasterone. While that might sound all scientificee, it's really just a name made up by Redefine Nutrition and filed as a trademark on March 12, 2012.

So what the heck is Decasterone? About the only info I can find comes from Redefine Nutrition itself, which, as far as I'm concerned, is akin to a high schooler grading his own paper. Nevertheless, here's what they say paraphrased and summed up:

"3b-enanthoxy-19-nor-androst-4-ene-17-one" is a new compound that's a two step precursor to 19nortestosteron. This conversion can (notice they say "can" and not "will") easily take place in the body as 3b-enanthoxy-19-nor-androst-4-ene-17-one --> 19norandrostenediol --> 19norTestosterone

This new compound is comprised of lipophilic ester (enanthate ester bond) at the 3-key position to not only to increase the stability of the compound, but also to increase purity.

The problem with other precursors to nandrolone like 19norDHEA, is two fold. During the final stage of the production process of regular 19norDHEA, purity is compromised due to the instability of the compound. Because 19norDHEA is very unstable during the final stage of reaction, some of the material in the reactor will be converted to other isomer and other unknown impurities.

The second issue with regular 19norDHEA is the delivery system. Regular 19norDHEA has a very short half life, which results in poor bioavailability.

Chemists at Redefine Nutrition have overcome both of these issues with this new compound, which maximizes both the purity to 99.9% and the bioavailability of the compound.

Main highlights of 3b-enanthoxy-19-nor-androst-4-ene-17-one mimics the benefits of nandrolone or 19nortestosterone. The term "19nor" means that a methyl group was removed from testosterone at a key position on its molecular backbone. This slight alteration of the chemical structure reduces the DHT related side effects (prostate issues, balding, zits) as well as the estrogenic side effects (gyno, man boobs, chesticles) that testosterone possesses.

So now you might be asking what the heck is 19nor? The 19-nor steroids are a group of compounds that are precursors to nandrolone. The chemical structure of the 19-nors differs from the more familiar and naturally prevalent androstenes and testosterone by the absence of the number 19 carbon atom and its attached hydrogen atoms. The removal of this chemical group results in a much flatter three-dimensional structure. That structural change in turn results in much more favorable binding affinities for skeletal muscle rather than for prostate and other sexual tissues. This is important because a high binding affinity means that a substance is more likely to enter the cell and bring about the desired effects.

Nandrolone (also known as 19-nortestosterone), the substance into which the 19-nors are to some extent converted by the liver, has a binding affinity that is not only high for skeletal muscle, but that is roughly equal for skeletal muscle and sexual tissues such as the prostate. In comparison, testosterone has a binding affinity as much as 50 times greater for sexual tissues (thus its greater "androgenicity") than for muscle. So, nandrolone has anabolic effects (which take place in muscle) but less androgenic effects (which occur in sexual tissues).

While there are still many facts not yet known about the 19-nors, we can tell you straight away that they do not compare in potency to the infamous illegal steroid known as Deca-Durabolin (nandrolone decanoate). The 19-nors may well be partly metabolized to 19-nortestosterone (nandrolone), the steroid base for Deca, but they're a far cry from

Info links for 3b-enanthoxy-19-nor-androst-4-ene-17-one (Decasterone)

Androsta-3,5-Diene-7,17-Dione (Arimistane)

This is being marketed as an Armoatase Inhibitor (AI) and cortisol inhibitor.

It's a metabolite of 7-Keto DHEA. The usual dosage of 7 Keto is 100-200mg, but this is not 7 Keto, it is 7 Keto DHEA. They're different.

This from Patrick Arnold over at Prohormoe Forum.com:
"The whole family of 7-oxygenated dhea metabolites are fascinating compounds, for many reasons other than aromatase inhibition. The compound under discussion here is not a major metabolite though, and so its very unlikely you could acheive therapeutic drug levels in your body by ingesting any reasonable amount of 7-keto"

From all the research I did, it would appear as though the jury is still out on this as far as to whether or not it actually does what the marketers claim.

There were some in vitro (lab test) that show AI properties, but no studies yet as to whether or not it translates into real life.

Bergamottin

Bergamottin is a natural furanocoumarin found principally in grapefruit juice. It is also found in the oil of bergamot, from which it was first isolated and from which its name is derived. To a lesser extent, bergamottin is also present in the essential oils of other citrus fruits. Along with the chemically related compound 6,7-dihydroxybergamottin, it is believed to be responsible for the grapefruit juice effect in which the consumption of the juice affects the metabolism of a variety of pharmaceutical drugs.

6,7-dihydroxy Bergamottin (6,7-DHB) is a potent inhibitor of CYP3A4 (IC50 = 25 M). It appears to be the primary compound in grapefruit juice that is responsible for inhibition of testosterone 6-hydrolase activity. Ingestion of grapefruit juice during treatment regimes with drugs normally metabolized by cytochrome P450 enzymes of the CYP3A subfamily results in a substantial increase in plasma concentration of these agents. However, giving a patient grapefruit juice or just 6,7-DHB could be advantageous in cases where a drug is metabolized too quickly by CYP3A4.

Info links for Bergamottin

Blue #1 (Food Coloring)

Also known as Blue #1, Brilliant Blue FCF

Blue # 1 is a colorant for foods and other substances to induce a color change. It is a synthetic dye produced using aromatic hydrocarbons from petroleum.permitted. It can also appear as an aluminium lake.

The dye is poorly absorbed from the gastro-intestinal tract and 95% of the ingested dye can be found in the feces.

Blue #1 has previously been banned in Austria, Belgium, Denmark, France, Germany, Greece, Italy, Norway, Spain, Sweden, and Switzerland among others, but has been certified as a safe food additive in the EU and is today legal in most of the countries. It has the capacity for inducing an allergic reaction in individuals with pre-existing moderate asthma.

It is one of the colorants that the Hyperactive Children's Support Group and the Feingold Association recommends to be eliminated from the diet of children. After extensive testing, the National Institutes of Health concluded that color additives do not cause hyperactivity.

Gelatin

Gelatin is a tasteless substance created from collagen found in animal skin and bones. It is used to thicken liquid in processed foods as well as having applications in photography, cosmetics, and pharmaceuticals. Gelatin is found in many forms of candy, marshmallows, Jell-O, and some types of yogurt. Gelatin can be bought in many grocery stores for use in home cooking. In the vast majority of cases, gelatin is not harmful to the consumer.

Magnesium Stearate

Magnesium stearate is often used as a diluent in the manufacture of medical tablets, capsules and powders. In this regard, the substance is also useful, because it has lubricating properties, preventing ingredients from sticking to manufacturing equipment during the compression of chemical powders into solid tablets.

Magnesium stearate is the most commonly used lubricant for tablets. Studies have shown that magnesium stearate may affect the release time of the active ingredients in tablets, but not that it reduces the over-all bioavailability of those ingredients.

Info links for Magnesium Stearate

Maltodextrin

Maltodextrin is a polysaccharide that is used as a food additive. It is produced from starch by partial hydrolysis and is usually found as a creamy-white hygroscopic spraydried powder. Maltodextrin is easily digestible, being absorbed as rapidly as glucose, and might be either moderately sweet or almost flavorless. It is commonly used for the production of natural sodas and candy.

Milk Thistle (SILYMARIN)

The milk thistle is a thistle of the genus Silybum Adans., a flowering plant of the daisy family (Asteraceae). They are native to the Mediterranean regions of Europe, North Africa and the Middle East. The name "milk thistle" derives from two features of the leaves: they are mottled with splashes of white and they contain a milky sap.

The seeds of the milk thistle have been used for 2000 years to treat chronic liver disease and protect the liver against toxins. Increasing research is being undertaken on the physiological effects, therapeutic properties and possible medical uses of milk thistle.

Research into the biological activity of silymarin and its possible medical uses has been conducted in many countries since the 1970s. Milk thistle has been reported to have protective effects on the liver and to greatly improve its function. It is typically used to treat liver cirrhosis, chronic hepatitis (liver inflammation), toxin-induced liver damage, and gallbladder disorders.

Reviews of the literature covering clinical studies of silymarin vary. A review using only studies with both double-blind and placebo protocols concluded that milk thistle and its derivatives "does not seem to significantly influence the course of patients with alcoholic and/or hepatitis B or C liver diseases".

A different review of the literature performed for the U. S. Department of Health and Human Services found that while there is strong evidence of legitimate medical benefits, the studies done to date are of uneven design and quality that no firm conclusions about degrees of effectiveness for specific conditions or appropriate dosage can yet be made.

A review of studies of silymarin and liver disease which are available on the web shows an interesting pattern in that studies which tested low dosages of silymarin concluded that silymarin was ineffective[13], while studies which used significantly larger doses concluded that silymarin was biologically active and had therapeutic effects.

Beside benefits for liver disease, other unproven treatment claims include:

Used as a post (oral steroid) cycle therapy for body builders and/or in the hopes of reducing or eliminating liver damage

Lowering cholesterol levels

Reducing insulin resistance in people with type 2 diabetes who also have cirrhosis

Reducing the growth of cancer cells in breast, cervical, and prostate cancers.

Used in many products claiming to reduce the effects of a hangover

Used by individuals withdrawing from opiates, especially during the Acute Withdrawal Stage.

Reducing liver damaging effects of chemotherapeutic drugs

Clinical study has shown that liver function tests can be improved in active hepatitis patients.

Info links for Milk Thistle (SILYMARIN)

N-acetyl-L-cysteine (NAC)

Acetylcysteine, also known as N-acetylcysteine or N-acetyl-L-cysteine (abbreviated NAC), is a pharmaceutical drug and nutritional supplement used primarily as a mucolytic agent and in the management of paracetamol (acetaminophen) overdose. Other uses include sulfate repletion in conditions, such as autism, where cysteine and related sulfur amino acids may be depleted.

Cysteine is an amino acid that can be found throughout the body. N-acetyl-L-cysteine (NAC), a modified form of cysteine, has been shown to increase levels of the antioxidant glutathione. Antioxidants such as glutathione can reduce cell damage, speed recovery from injury and aid muscle growth.

NAC is a popular supplement with a wide variety of uses. Because it reduces muscle damage and strengthens the immune system, NAC is used by endurance athletes such as long-distance runners, cyclists and triathletes. Many athletes include NAC in their diet when they are in the early stages of recovering from an injury.

The anabolic effect of NAC on muscle tissue also makes it popular with athletes wanting to gain lean muscle size and strength, including body builders, rugby players, and sprinters.

Info links for N-acetyl-L-cysteine (NAC)

Naringin

Naringin belongs to the group of flavonoids, a conjugate of a sugar molecule with naringenin. Pure naringin is a yellowish powder. The structure of naringin is very similar to that of hesperidin.

Studies have shown naringin to have a cholesterol-lowering effect, reduces LDL oxiation and can help to prevent hypercholesterolemia. Studies in rats found that diets supplemented with red grapefruit juice and to a lesser degree with naringin improved the plasma lipid levels mainly in rats fed cholesterol and increased the plasma antioxidant activity. The conclusion was that naringin has plasma lipid lowering and plasma antioxidant activity increasing activity.

Naringin is an aldose reductase inhibitor which means that it can help to fight retinal disease linked to diabetics.

Naringin (and grapefruit) can interfere with certain drugs including calcium channel blockers, sedatives, cholesterol lowering drugs, caffeine and estrogen. Naringin stimulates the effect of caffeine and could therefore increase its fat burning action.

Red #40 (Food Coloring)

Also known as Allura Red AC, Food Red 17, C.I. 16035, and Red 40. It is used as a food dye. Allura Red AC was originally introduced in the United States as a replacement for the use of amaranth as a food coloring.

Red 40 was originally manufactured from coal tar but is now mostly made from petroleum. Despite the popular misconception, Allura Red AC is not derived from any insect, unlike the food colouring carmine which is derived from the female cochineal insect.

Allura Red AC has fewer health risks associated with it in comparison to other azo dyes. However, some studies have found some adverse health effects that may be associated with the dye.

In Europe, Allura Red AC is not recommended for consumption by children. It is banned in Denmark, Belgium, France, Switzerland, and Sweden. The European Union approves Allura Red AC as a food colorant, but EU countries' local laws banning food colorants are preserved. In Norway, it was banned between 1978 and 2001, a period in which azo dyes were only legally used in alcoholic beverages and some fish products.

In the United States, Allura Red AC is approved by the Food and Drug Administration (FDA) for use in cosmetics, drugs, and food. It is used in some tattoo inks and is used in many products, such as soft drinks, children's medications, and cotton candy. On June 30, 2010, the Center for Science in the Public Interest (CSPI) called for the FDA to ban Red 40. Executive Director Michael Jacobson said, "These synthetic chemicals do absolutely nothing to improve the nutritional quality or safety of foods, but trigger behavior problems in children and, possibly, cancer in anybody."

Silicon Dioxide (Silica)

The chemical compound silicon dioxide, also known as silica, is an oxide of silicon. Silica is most commonly found in nature as sand or quartz.

Silica is common additive in the production of foods, where it is used primarily as a flow agent in powdered foods, or to absorb water in hygroscopic applications. It is the primary component of diatomaceous earth which has many uses ranging from filtration to insect control. It is also the primary component of rice husk ash which is used, for example, in filtration and cement manufacturing.

Info links for Silicon Dioxide (Silica)

Titanium Dioxide

Titanium dioxide, also known as titanium(IV) oxide or titania, is the naturally occurring oxide of titanium. When used as a pigment, it is called titanium white, Pigment White 6, or CI 77891. It has a wide range of applications, from paint to sunscreen to food colouring. When used as a food colouring, it has E number E171.

Titanium dioxide may be used in food to give opacity. No adverse effects are known, and the compound is chemically inert. Typical products include sweets, pharmaceutical tablets and vitamin supplements, sauces and cheese.

Vitamin C (Ascorbic Acid)

Vitamin C is a water-soluble vitamin necessary for normal growth and development. Water-soluble vitamins dissolve in water. Leftover amounts of the vitamin leave the body through the urine. That means you need a continuous supply of such vitamins in your diet.

Vitamin C is necessary to form collagen, an important protein used to make skin, scar tissue, tendons, ligaments, and blood vessels. It's also essential for healing and repair and maintenance of cartilage, bones, and teeth.

Vitamin C is an antioxidant. Antioxidants are nutrients that block some of the damage caused by free radicals, which are by-products that result when our bodies transform food into energy. The build up of these by-products over time is largely responsible for the aging process and can contribute to the development of various health conditions. Antioxidants also help reduce the damage to the body caused by toxic chemicals and pollutants.

The body does not manufacture Vitamin C, nor does it store it. It is therefore important to include plenty of vitamin C-containing foods in your daily diet.

All fruits and vegetables contain some Vitamin C. The highest sources of vitamin C include green peppers, citrus fruits and juices, strawberries, tomatoes, broccoli, turnip greens and other leafy greens, sweet and white potatoes, cantaloupe, papaya, mango, watermelon, brussels sprouts, cauliflower, cabbage, winter squash, red peppers, raspberries, blueberries, cranberries, and pineapples.
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A! Supplements Finaflex 550-XD - $53.95 (8/22/2012)
Amazon Finaflex 550 $80.00 (12/18/2012)
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