Cycle Assist Information (On Cycle Support)

Cycle Assist by


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Ingredients
Manufactured by:
Competetive Edge Labs (CEL)

Serving Size
4 capsule
Servings per Container
60

Amount Per Serving
N-Acetyl-l-Cysteine (NAC) 750mg
Milk Thistle (Standardized to 80% Silymarin) 500mg
Pantothenic Acid (Vitamin B5) 500mg
Hawthorn Berry Extract (Standardized to 1.8% Vitexin) 300mg
Vitamin B6 (Pyridoxine HCl) 200mg
Saw Palmetto Extract (Standardized to 45% Fatty Acids) 160mg
Celery Seed Extract (10:1) 75mg
Grape Seed Extract (95% Proanthocyanidins) 75mg
Policosanol 20mg
Zinc Gluconate 15mg

Bottle recommended dosage: Take 4 capsules twice daily spaced out 8 to 12 hours apart, preferably with meals.

Cycle Assist is designed to be an all-in-one support solution for basic on-cycle and post-cycle therapy needs related to the used ot prohormone, steroids and other heptoxic compounds.

Cycle Assist contains a combination of ingredients reputed to provide liver, blood pressure, cholesterol, prostate, and acne support.

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Celery Seed

Celery seed isn't well-known in Western herbal medicine, although it's been used for thousands of years in other areas of the world. Celery seed has been used to treat colds, flu, water retention, poor digestion, various types of arthritis, and some diseases of the liver and spleen.

In modern times, celery seed is used primarily as a diuretic to increase urine output to help the body get rid of excess water. Celery seed has also been used for treating arthritis and gout, to help reduce muscle spasms, calm the nerves, and reduce inflammation.

It should be noted, however, that there aren't any scientific studies in humans that show whether celery seed is effective for these conditions or any others. Studies have confirmed that celery seeds act as a mosquito repellent.

A few animal studies suggest that celery seed extracts may help lower blood pressure and cholesterol, as well as protect the liver from damaging substances such as the pain reliever acetaminophen. Animal studies also show celery seed may help prevent the formation of cancerous tumors in mice.

In humans, researchers have found that people who eat a diet rich in lutein (found in celery, spinach, broccoli, lettuce, tomatoes, oranges, carrots, and greens) were significantly less likely to develop colorectal cancer. However, celery was just one part of their diet, and no one knows whether the effect is due to celery, another food, or some combination of foods.

Celery seeds contain volatile oils, flavonoids (plant pigments with antioxidant effects that may protect cells from damage), coumarins (chemical compounds that help thin the blood), and linoleic acid (an omega-6 fatty acid).

Grape Seed Extract

Grape seed extracts are derivatives from whole grape seeds that have a concentration of vitamin E, flavonoids, linoleic acid, and OPCs.

Preliminary studies in humans and animals show grape seed extract may be useful to treat high blood pressure and high cholesterol. By limiting lipid oxidation, phenolics in grape seeds may reduce risk of heart disease, such as by inhibiting platelet aggregation and reducing inflammation. A polyphenol contained in grape seeds is resveratrol which may interfere with cancer cell growth and proliferation, as well as induce apoptosis, among a variety of potential preventive effects.

Currently, there are clinical trials underway to assess the effect of grape seed extracts on human breast cancer, blood estrogen levels in postmenopausal women, and coronary artery disease.

Of note to strength athletes, grape seed extract is also an aromatase inhibitor; it suppresses the conversion of testosterone to estradiol.

Hawthorne Berry

Used to promote the health of the circulatory system, treat angina, high blood pressure, congestive heart failure and cardiac arrhythmia and has been found to strengthen the heart. Hawthorn has also been indicated for strengthening blood vessels, vascular insufficiency and blood clots, restoring the heart muscle wall, lowering cholesterol and to aid digestion. Hawthorn is endorsed by Commission E - the branch of the German government that studies and approves herbal treatments.

There is evidence for cardiovascular system improvement, particularly in clinical parameters associated with angina, congestive heart failure and acute myocardial infarct. Its use in the treatment of hepatitis in modern Chinese medicine is supported by the demonstration of hepatoprotective activity in animal studies.

Milk Thistle (SILYMARIN)

The milk thistle is a thistle of the genus Silybum Adans., a flowering plant of the daisy family (Asteraceae). They are native to the Mediterranean regions of Europe, North Africa and the Middle East. The name "milk thistle" derives from two features of the leaves: they are mottled with splashes of white and they contain a milky sap.

The seeds of the milk thistle have been used for 2000 years to treat chronic liver disease and protect the liver against toxins. Increasing research is being undertaken on the physiological effects, therapeutic properties and possible medical uses of milk thistle.

Research into the biological activity of silymarin and its possible medical uses has been conducted in many countries since the 1970s. Milk thistle has been reported to have protective effects on the liver and to greatly improve its function. It is typically used to treat liver cirrhosis, chronic hepatitis (liver inflammation), toxin-induced liver damage, and gallbladder disorders.

Reviews of the literature covering clinical studies of silymarin vary. A review using only studies with both double-blind and placebo protocols concluded that milk thistle and its derivatives "does not seem to significantly influence the course of patients with alcoholic and/or hepatitis B or C liver diseases".

A different review of the literature performed for the U. S. Department of Health and Human Services found that while there is strong evidence of legitimate medical benefits, the studies done to date are of uneven design and quality that no firm conclusions about degrees of effectiveness for specific conditions or appropriate dosage can yet be made.

A review of studies of silymarin and liver disease which are available on the web shows an interesting pattern in that studies which tested low dosages of silymarin concluded that silymarin was ineffective[13], while studies which used significantly larger doses concluded that silymarin was biologically active and had therapeutic effects.

Beside benefits for liver disease, other unproven treatment claims include:

Used as a post (oral steroid) cycle therapy for body builders and/or in the hopes of reducing or eliminating liver damage

Lowering cholesterol levels

Reducing insulin resistance in people with type 2 diabetes who also have cirrhosis

Reducing the growth of cancer cells in breast, cervical, and prostate cancers.

Used in many products claiming to reduce the effects of a hangover

Used by individuals withdrawing from opiates, especially during the Acute Withdrawal Stage.

Reducing liver damaging effects of chemotherapeutic drugs

Clinical study has shown that liver function tests can be improved in active hepatitis patients.

N-acetyl-L-cysteine (NAC)

Acetylcysteine, also known as N-acetylcysteine or N-acetyl-L-cysteine (abbreviated NAC), is a pharmaceutical drug and nutritional supplement used primarily as a mucolytic agent and in the management of paracetamol (acetaminophen) overdose. Other uses include sulfate repletion in conditions, such as autism, where cysteine and related sulfur amino acids may be depleted.

Cysteine is an amino acid that can be found throughout the body. N-acetyl-L-cysteine (NAC), a modified form of cysteine, has been shown to increase levels of the antioxidant glutathione. Antioxidants such as glutathione can reduce cell damage, speed recovery from injury and aid muscle growth.

NAC is a popular supplement with a wide variety of uses. Because it reduces muscle damage and strengthens the immune system, NAC is used by endurance athletes such as long-distance runners, cyclists and triathletes. Many athletes include NAC in their diet when they are in the early stages of recovering from an injury.

The anabolic effect of NAC on muscle tissue also makes it popular with athletes wanting to gain lean muscle size and strength, including body builders, rugby players, and sprinters.

Policosanol

Policosanol is a mixture of waxy substances usually manufactured from sugarcane containing about 60% octacosanol, along with related chemicals. In some cases, the terms octacosanol and policosanol are used interchangeably.

Several studies have reported sugarcane policosanol can improve cholesterol profile. Policosanol has been approved as a treatment for high cholesterol in about two dozen countries, most of them in Latin America. It should be noted that all positive studies of policosanol were performed and reported by a single Cuban research group, a group that has a financial relationship to the product.

Independent studies of sugarcane policosanol showed policosanol proved more effective than placebo.

The tested Cuban policosanol product is manufactured from sugarcane. Octacosanol and related substances are also found in wheat germ oil, vegetable oils, alfalfa , and various animal products.

Due to political and patent issues, sugarcane policosanol is not widely available in the US. Products sold in the US market as "policosanol" are generally derived from beeswax or wheat germ. These products have a significantly different mixture of constituents and could have substantially different effects.

Policosanol is one of the fastest growing over-the-counter supplements sold in the United States. The use of policosanol to treat elevated cholesterol is based on clinical trials conducted in Cuba, which showed sugar cane?derived policosanol to be similar in efficacy to statins. Recent studies have challenged these findings, but there have been no trials conducted in North America that have examined the ability of sugar cane?derived policosanol to lower cholesterol.

Saw Palmetto (SERENOA REPENS)

Saw palmetto (Serenoa repens, Sabal serrulata) is used popularly in Europe for symptoms associated with benign prostatic hypertrophy (enlargement of the prostate). Although not considered standard of care in the United States, it is the most popular herbal treatment for this condition. Saw palmetto is often combined with nettle extract.

Multiple mechanisms of action have been proposed, and saw palmetto appears to possess 5-?-reductase inhibitory activity (thereby preventing the conversion of testosterone to dihydrotestosterone). Hormonal/estrogenic effects have also been reported, as well as direct inhibitory effects on androgen receptors and anti-inflammatory properties.

Vitamin B5 (Pantothenic Acid)

B5 (aka Pantothenic acid, pantothenate, d-calcium panthothenate) is a water-soluble vitamin. Many animals require pantothenic acid to synthesize coenzyme-A, as well as to synthesize and metabolize proteins, carbohydrates, and fats.

Small quantities of pantothenic acid are found in nearly every food, with high amounts in whole-grain cereals, legumes, eggs, meat, royal jelly, avocado, and yogurt. It is commonly found as its alcohol analog, the provitamin panthenol, and as calcium pantothenate. Pantothenic acid is an ingredient in some hair and skin care products.

The derivative of pantothenic acid, pantothenol, is a more stable form of the vitamin and is often used as a source of the vitamin in multivitamin supplements. Another common supplemental form of the vitamin is calcium pantothenate. Calcium pantothenate is often used in dietary supplements. As a salt, it is more stable than pantothenic acid in the digestive tract, allowing for better absorption.

Doses of 2 g/day of calcium pantothenate may reduce the duration of morning stiffness, degree of disability, and pain severity from rheumatoid arthritis. Although the results are inconsistent, supplementation may improve oxygen efficiency and reduce lactic acid accumulation in athletes

Vitamin B-6

The primary role of vitamin B6 is to act as a coenzyme to many other enzymes in the body that are involved predominantly in metabolism. This role is performed by the active form, pyridoxal phosphate. This active form is converted from the two other natural forms founds in food: pyridoxal, pyridoxine and pyridoxamine.

Vitamin B6 is involved in the following metabolic processes:

amino acid, glucose and lipid metabolism

neurotransmitter synthesis

histamine synthesis

hemoglobin synthesis and function

gene expression

Amino acid metabolism

Pyridoxal phosphate is involved in almost all amino acid metabolism, from synthesis to breakdown.

Neurotransmitter synthesis

Pyridoxal phosphate-dependent enzymes play a role in the biosynthesis of four important neurotransmitters: serotonin, epinephrine, norepinephrine and gamma-aminobutyric acid. Serine racemase, which synthesizes the neuromodulator D-serine, is also a pyridoxal phosphate-dependent enzyme.

Histamine synthesis

Pyridoxal phosphate is involved in the metabolism of histamine.

Hemoglobin synthesis and function

Pyridoxal phosphate aids in the synthesis of heme and can also bind to two sites on hemoglobin to enhance the oxygen binding of hemoglobin.

Gene expression

It transforms homocysteine into cistation then into cysteine. Pyridoxal phosphate has been implicated in increasing or decreasing the expression of certain genes. Increased intracellular levels of the vitamin will lead to a decrease in the transcription of glucocorticoid hormones. Also, vitamin B6 deficiency will lead to the increased expression of albumin mRNA. Also, pyridoxal phosphate will influence gene expression of glycoprotein IIb by interacting with various transcription factors. The result is inhibition of platelet aggregation.

Zinc Gluconate

Zinc gluconate is another form of zinc used to make zinc supplements. Amino acid chelates of zinc may be the best form of zinc supplementation, but they can be expensive. SZinc sulfate has been known to cause stomach irritation. Zinc gluconate is a good type and is absorbed well.

The RDA for zinc is 15 milligrams for men, 12 for women, 3 for infants, 10 for children ages 1 to 10, 15 for pregnant women and 16 to 19 for those nursing. It's recommended that adults, especially athletes, take 30 milligrams daily. Dosages of up to 50 milligrams a day are considered safe, but higher levels aren't recommended. Older people don't absorb zinc as well and thue might need more.

It's also suggested that you supplement with copper along with zinc, about 1 milligram of copper for every 10mgs of zinc. Taking 50 to 200 micrograms of selenium is suggested as well.

The best food sources for zinc include brewers yeast and wheat brand or germ (this may be the reason that many bodybuilders have had good results with these), whole grains and oysters.

Testosterone is known to be closely interrelated with zinc. Although research still needs to be done, it appears zinc may govern testosterone metabolism at the cellular level. It is also thought to control the metabolism of testosterone in the prostate.

Double blind studies have shown that zinc can increase blood levels of testosterone and the follicle-stimulating hormone in men with just very mildly deficient zinc
levels. Males with just mild zinc deficiency will increase their plasma levels of testosterone with zinc supplementation. For about 25 cents a week you can take what may be the most powerful legal and natural 'anabolic' supplement.

Another aspect of zinc is it's role in glucose tolerance. In tests with rats, when zinc is removed from their diet, glucose intolerance develops. In human studies of diabetics, it has been shown that many have problems absorbing zinc and over excrete it as well.