Androdrol Information (Prohormones)

Androdrol by Powerlab Nutrition


Ratings
Ingredients
Manufactured by:
PowerLab Nutrition

Serving Size: 1 Capsule
Servings Per Container: 60

Amount Per Serving:
4-chloro-17a-methyl-androst-1,4-diene-3-17b-diol 20mg
2a,3a-epithio-17a-methyl-5a-androstan-17b-ol 15mg
13-ethyl-3-methoxy-gona-2,5(10)dien-17-one 15mg
2a-17a-dimethyl-17b-hydroxy-5a-androstan-3-one 10mg
6 bromoandrostenedione 50mg

ABSORBTECH Delivery System 10mg
Bioprene
Vanadyl Sulfate

Bottle recommended dosage: 1 capsule two times daily, approx. 6 hrs apart - do not exceed more than 2 capsules per 24 hour period. Do not use Androdrol for more than 8 weeks continuously.

Whoa, you've got a stack of stuff here:
20mg Halovar
15mg Epistane
15mg Max LMG
10mg Superdrol

The 6 bromoandrostenedione is supposed to be an anti-estrogen.

And that's one pill. I've read Superdrol logs where users make great gains running standalone Superdrol at 20mg a day. Same goes for users running 30mg a day of Epistane. Here're you've got a recommended dosage that has you taking 40mg Halover (a Halodrol clone), 30mg Epistane, 30mg Max LMG, and 20mg Superdrol. And they say it's OK to take for 8 weeks!

While I'm sure you'd see some positive effects from that as far as gains, I've got to image the sides would be a bear. Most standalone Superdrol runs are 4 weeks or less.

Remember, slow and steady wins the race, run too fast you might fall on your face. I can't think of any reason to stack 4 designer steroids, and, even if I could, I'd probably buy each one seperately so I could have more control over the dosage.

If you try this, don't exceed the recommended dosage (2 pills per day) and don't run longer than 4 weeks. Get liver values tested BEFORE running, and then 2 weeks in. Take your liver support and have a good PCT lined up.

Personally, I wouldn't take it--it's just too hardcore for me. Most of what I read on the boards seem to feel the same way I do.

The official company write-up:
In 2009, Powerlab Nutrition introduced the end all of steroid precursors. Produced only for the most hardcore bodybuilders and strength athletes. Androbol was an instant sensation. Users were seeing gains of over 20lbs. of muscle mass in 8 weeks. Naturally, when word got out about the phenomenal gains, the FDA and DEA were quick to act and banned one of the chemical compounds in Androbol as a schedule III anabolic steroid beginning Jan 4, 2010.

So in 2010, Powerlab Nutrition will introduce our next anabolic sensation, Androdrol. The same chemical precursors as Androbol except one which has been replaced by the Epistane chemical compound (a muscle hardener) (PHDB insert: Epistane is an actual steroid, not a precursor and not a 'muscle hardener'). Of course, Androdrol also contains our patented ABSORBTECH delivery system that allows for virtually 100% absorption (PHDB insert: unproven). Androdrol also contains an anti-estrogen to eliminate water weight and and any possible side effects (PHDB insert: the anti-estrogen effects of 6 Bromo are yet to be clinically proven in humans, as is it's ability to mitigate andrgen sides from steroids and steroid precursors).

Member Rating for Androdrol
Strength (higher = better)Size (higher = better)
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Current Rating: 8.2
Current Rating: 6.8
Cutting (higher = better)Sides (lower = better)
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Current Rating: 5.8
Current Rating: 4.4
Overall Rating: 6.85 (higher is better)

13-ethyl-3-methoxy-gona-2,5(10)diene-17-one (Max LMG)

Trade names include Max LMG, Tren, Trena, AKA Methoxygonadiene

Common dosage: 60-120mg daily
Common cycle length: 4-6 weeks
Methylated: No
Half-Life:Long (48-72 hours)

Not a 17aa steroid so liver toxicity is not as harsh as with 17aa steorids, however the ethyl group on C-18 may make it slightly more toxic than a non-ethylated steroid (while increasing its oral bio-availability). Max LMG is progestin designed to give solid gains in muscle mass with low water retention. The progestational activity of methoxygonadiene (once it is converted to its active metabolites) is considered to be slightly stronger than nandrolone. This means muscle building with Max LMG in your cycle gives you higher quality hardening effects. Since it acts as anti-progesterone, there are decreased negative effects of extra estrogen and increased libido.

It is legal because it is a progestin, like trenbolone, nandrolone, methyltrienolone and Methyl-Dien. As a progestin, Max LMG is structurally related to the pill RU-486 and as such acts as an "anti-progesterone". This results in decreased estrogen-like effects and an increase in libido.

Research suggests that Max LMG has a half-life of about 6 hours, though it appears that it is closer to 10 hours based upon plasma levels maintained in test subjects. It is not a 17-alkylated analog and has a low potential for liver toxicity.

Most users report good results at a dosage of 75mg a day.

Some comments from users:

"As stated, appears to be an all out bulker. Great for size and strength, but notorious for bloat and the potential for gyno. I've also read that it kills libido pretty quickly. Some of the makers claimed that the libido would remain fine if one didn't use too large of daily doses though. I remember seeing people getting decent gains from 40mg - 50mg (depending on the product). It looks like most guys go up to 75mg though."

"Would be my favorite if it didn't make my nips start burning by the end of week two. Rapid weight gain on it plus the fact its not methyl are pluses. Just keep in mind i've seen many complain about it easily aggrevating gyno."

In the stomach acid, the C-3 methoxy group is rapidly cleaved off and the double bond on the A ring at C-2 is lost. At this point, a 3-oxo is formed and a metabolite known as 13b-ethyl-nor-androstenedione is created, which is chemically similar to norbolethone, and probably where this compound gets most of its effects.

13b-ethyl-nor-androstenedione is about equal to testosterone in anabolic potency, yet less androgenic. This would make this compound fairly light on the hairline with minimal chance of acne or other androgenic side-effects.

With low androgenic activity, this compound may negatively affect the libido and erectile function. The lack of androgenic potency and progestational effects make this compound likely to cause gyno symptoms. Users could stack this compound with testosterone or one of its non-aromatizing metabolites to preserve DHT levels and possibly prevent these side-effects.

Users experience rapid weight gain from this compound partly due to subcutaneous water retention from the progestational activity. Therefore the overall gains from this compound may lead to a bloated appearance. Because of the progestational effects, users should avoid stacking this compound with other gyno aggravating compounds. Max LMG can aromatize to estrogen in small amounts, however not to any significant degree, therefore an aromatase inhibitor would provide little protection against this compound's side-effects.

Max LMG immediately converts in the stomach into a 13b alkylated compound (13b ethyl nor androstenedione) and then makes it all the way to the liver because it is ethylated to survive first pass, and is converted into 13b ethyl nor testosterone, a steroid similar to norbolethone aka the clear.

2a,17a-dimethyl-17b-Hydroxy-5a-androstan-3-one (Superdrol)

Yet another nomenclature for Superdrol.

2a,17a-dimethyl-17b-hydroxy-5a-androstan-3-one and 2a,17a-di-methyl-etiocholan-3-one,17b-ol are the same exact compounds written differently. They are both methylated at the 2a and 17a positions, both have a hydroxyl (alcohol, -OH) group at the 17b potion, and a ketone at position three. Just one attempts to use the term etiocholan, which isn't used too often.

2a,17a-dimethyl-17b-hydroxy-5a-androstan-3-one is a derivative of Drostanolon (also called Dromostanolone), which is also known as the commercial AAS Masteron. Drostanolon has a chemical structure of 2a-methyl-17b-hydroxy-5a-androstan-3-one. Drostanolon is the 2-methylated form of DHT, so it has typically been used for reducing body-fat and water retention, while increasing muscle hardness and density, as it cannot form estrogen.

2a,17a-dimethyl-17b-hydroxy-5a-androstan-3-one is a derivative of Drostanolon, except it is a di-methyl instead of a methyl. It has one methyl in the 17th position, just like M-1-t and M-Dien, but it also has a 2nd methyl in the 2nd position.

This is how the derivative is different from standard Drostanolon, in that it has another methyl in the 17th position. Standard Drostanolon has one in the 2nd position, and not the 17th like M-1-t.

Also, it is a saturated modified form of anadrol, so you get the best of both worlds without the progesterone, estrogen, bloat, hypertension problems with anadrol.
Zero estrogen conversion, because it's 5-reduced and A-ring alkylated. Also, the parent compound (masteron) is used exclusively as an anti-neoplastic for metastatic breast cancer, so it's a strong anti-estrogen.

The chemical has been named methasteron and the product Supderdrol.

2a,3a-epithio-17a-methyl-5a-androstan-17b-ol (Havoc/Epistane)

Also written as: 2a,3a-epithio-17a-methyl-17b-hydroxy-5a-adrostan

Trade names include Havoc/Epistane
Common Dosages: 30mg to 40mg daily
Common Cycle Length: 4-5 Weeks
Methylated: Yes
Half-Life: Average (6-8 hours)

A designer steroid and legal alternative to anabolic and androgenic steroids.

Epistane is a methylated version of the controlled substance Epitiostanol (2,3-Epithio-5-androstan-17-ol), created in the 1960's and used as a treatment for breast cancer. Chemists added a methyl group to the compound to create the product known as Epistane. Epistane is a sulfur containing steroid which is known to have strong and long lasting anti-estrogenic activity as well as weak androgenic and mytropic activities.

Since it is anti-estrogenic, you can expect very dry gains from this compound. Epistane has low androgenic to anabolic activity, meaning it is much more anabolic then androgenic. Even though users will see dry gains on Epistane it does not mean that it would be any insufficient for a bulking cycle.

Side effects are typically minimal to non existent.

4-chloro-17a-methyl-androst-1,4-diene-3-17b-diol (Halovar)

A clone of Halodrol (4-chloro-17a-methyl-androst-1, 4-diene-3b,17b-diol)

Halodrol is a 17aa steroid that converts to the steroid oral Turinabol after interaction with 3b-HSD at an estimated rate of about 5%. Because of this low conversion, doses must be higher than other 17aa pro-steroids. However, it is suspected that Halodrol has decent potency without conversion as good results are seen despite the relatively low conversion to Turinabol. Halodrol appears to be about as potent as testosterone, and significantly less androgenic.

Because of the 4-chloro group, halodrol has no progestational effects, it cannot interact with the aromatase enzyme, and it produces inactive 4-chloro-DHT metabolites. This makes androgenic side-effects such as hair loss, high blood pressure, acne and prostate enlargement less likely.

The lack of androgenic potency might be expected to create problems with gyno, however the low SHBG binding affinity has minimal interference with SHBG levels and/or freely circuiting estrogen and testosterone. It does not appear that halodrol has a significant gyno risk.

Because halodrol must be used at such a high dose to see noticeable effects, liver toxicity may become an issue. Therefore it is recommended to use a liver protecting supplement before and during halodrol cycles.

Gains from Halodrol generally take a few weeks to notice, but users can expect solid increases in strength, lean muscle mass, improved vascularity and minimal water retention. This allows some of the gains to be kept after the cycle if good diet and training are continued. Quick dramatic gains in size and strength are not generally noticed with Halodrol.

H-Drol is one of the most popular and proven compounds on the market and is considered good for beginners due to it's reputation for minimal side effects and dry gains that are relatively easy to maintain after the cycle is complete.

6-Bromoandrostenedione

I've been confusing myself again.

There's the compound 6-Bromodione which binds to the aromatase enzyme making it unable to convert androgens to estrogen.

6-alpha-Bromodione is a fast acting competitive inhibitor of the aromatase enzyme. It works by binding to the aromatase enzyme to prevent it from aromatizing androgens. This is not a permanent binding and later acts to normalize aromatase (and thus estrogen levels) as hormone production returns to normal. It specifically targets aromatase and does not act as a central anti-androgen like some other post cycle products can. This means that your libido and mood will not be negatively affected.

6-beta-Bromodione works in a similar way but has an irreversible and permanent effect. This works well to mediate the excess aromatase that was produced while on cycle, while the alpha isomer works to normalize the natural levels. The goal is again to transition into normal production levels for all hormones affected by the anabolic cycle.

I found "6-bromoandrostenedione vs. 6 Bromodione" and says: "They are the same thing; I think it also goes by "6-bromolane. I would imagine that products containing 6-bromodione would be a mixture of alpha and beta, given the expense associated with separation. Also, 6-alpha-bromodione should convert into 6-alpha-bromo-testosterone, which should be a relatively potent anabolic steroid. So, if taken for PCT, it could actually be suppressive (like epistane, which is both an AI and suppressive steroid). Actually, I bet 6-alpha-bromodione would make a decent PH.

I think 4-HO-androstenedione has been researched more, but both could probably lower androstenedione production."

Bioprene

Bioperine is a standardized extract from the fruits of Piper nigrum L (black pepper) or Piper longum L (long pepper). It contains a minimum piperine content of 95% compared to the 3-9% and 3-5% found in raw forms of Piper nigrumand and Piper longum respectively. Bioperine may be administered with various nutrients to assist in the uptake and utilization of those nutrients.

Bioperine is the only source of piperine to obtain patented status for its ability to increase the bioavailability of nutritional compounds. Bioperine is also the only source of piperine to undergo clinical studies in the U.S. to substantiate its safety and efficacy for nutritional use. When Bioperine was administered orally to healthy humans in a dose of 5 mg per person per day, the serum levels of different tested nutrients significantly increased by up to 60%.

Vanadyl Sulfate

Vanadyl Sulfate is the most popular and common form of vanadium, an element in the body that is found in foods such as pepper, dill, radishes, eggs, vegetable oils, buckwheat, and oats.

The physiological role of vanadium in humans is unknown, but it seems that the substance is needed for normal growth and development. Recently, a great deal of attention has been paid to vanadium because of its supposed insulin-mimicking activities. The precise mechanism by which vanadium mimics the effects of insulin is uncertain. The most popular view has been that vanadium works as a cofactor that alters the concentration and effectiveness of several enzymes that are involved in the breakdown and distribution of glucose molecules and amino acids.

The lack of research into the specific methodology and structure of vanadium has left much up to speculation. Workout supplement suppliers have taken advantage of this condition by making bold claims.

Unfortunately, vanadyl sulfate doesn't live up to its claims. The theoretical benefits of increased amounts of insulin were extrapolated from the role of insulin after a large meal. During exercise, the role of insulin in the body is diminished. Insulin is no longer the primary regulator of glucose uptake. During exercise, more glucose is made available to the muscle cell due to an increased blood flow. The rapidly moving blood transports the glucose molecules and enables the rapidly consumed supply to be replenished as needed. An increase in insulin is simply not necessary.

In addition to overestimating the potential benefits of increased insulin like activity through vanadyl sulfate, it also appears that proponents of the supplement also overlooked some of the potential dangers. Insulin does much more than enable glucose and amino acid uptake in muscle cells; it is one of the body's primary regulatory hormones. In addition, insulin also helps to synthesize both protein and fat molecules.

In December of 1996, a research team at the School of Pharmacy at the University of Otago in New Zealand performed a study on the effects of oral vanadyl sulfate on body composition and athletic performance. In the twelve week, double-blind placebo controlled test, the results were astounding. To test the strength gains of the subjects, a strength baseline was established at the beginning of the study. In addition, subjects were measured for body fat percentage and overall lean body mass. At the beginning of the study, the strength of all participants was assessed using the 1 and 10 repetition maximum for bench press and leg press. Throughout the twelve week period, subjects worked out with a partner. One subject took vanadyl sulfate (.5mg/day) and the other took a placebo. At the end of the double-blind study, the researchers concluded that with regard to side effects, oral vanadyl sulfate appeared to be well tolerated, however, they also concluded that "oral vanadyl sulfate was ineffective in changing body composition in weight -training athletes".

Specifically, both groups gained (.07%) body fat and had almost identical strength gains.