2B-1 Pure Lean Mass Information (Prohormones)
Serving Size: 1 Capsule
Servings Per Container: 60
This stack can be taken as a 4, or 8-week cycle depending on desired results.
This ingredient panel is designed for professional and hardcore athletes, and should always be accompanied by a proper cycle support, and post cycle therapy.
Taken from the MadCat Supplements website:
2B-1 is an advanced muscle building stack designed for lean muscle gains, with very little water weight.
It is an intense 4-week cycle that combines proven muscle-building compounds like Halodrol, Methylstenbolone, LMG-Max, and Dimethazine. All of which have been on the market for quite some time, and all of which have received excellent results as expressed from most clients.
2B-1 Pure Lean Mass Ingredients
13-ethyl-3-methoxy-gona-2,5(10)diene-17-one (Max LMG)Trade names include Max LMG, Tren, Trena, AKA Methoxygonadiene
Common dosage: 60-120mg daily
Common cycle length: 4-6 weeks
Half-Life:Long (48-72 hours)
Not a 17aa steroid so liver toxicity is not as harsh as with 17aa steorids, however the ethyl group on C-18 may make it slightly more toxic than a non-ethylated steroid (while increasing its oral bio-availability). Max LMG is progestin designed to give solid gains in muscle mass with low water retention. The progestational activity of methoxygonadiene (once it is converted to its active metabolites) is considered to be slightly stronger than nandrolone. This means muscle building with Max LMG in your cycle gives you higher quality hardening effects. Since it acts as anti-progesterone, there are decreased negative effects of extra estrogen and increased libido.
It is legal because it is a progestin, like trenbolone, nandrolone, methyltrienolone and Methyl-Dien. As a progestin, Max LMG is structurally related to the pill RU-486 and as such acts as an "anti-progesterone". This results in decreased estrogen-like effects and an increase in libido.
Research suggests that Max LMG has a half-life of about 6 hours, though it appears that it is closer to 10 hours based upon plasma levels maintained in test subjects. It is not a 17-alkylated analog and has a low potential for liver toxicity.
Most users report good results at a dosage of 75mg a day.
Some comments from users:
"As stated, appears to be an all out bulker. Great for size and strength, but notorious for bloat and the potential for gyno. I've also read that it kills libido pretty quickly. Some of the makers claimed that the libido would remain fine if one didn't use too large of daily doses though. I remember seeing people getting decent gains from 40mg - 50mg (depending on the product). It looks like most guys go up to 75mg though."
"Would be my favorite if it didn't make my nips start burning by the end of week two. Rapid weight gain on it plus the fact its not methyl are pluses. Just keep in mind i've seen many complain about it easily aggrevating gyno."
In the stomach acid, the C-3 methoxy group is rapidly cleaved off and the double bond on the A ring at C-2 is lost. At this point, a 3-oxo is formed and a metabolite known as 13b-ethyl-nor-androstenedione is created, which is chemically similar to norbolethone, and probably where this compound gets most of its effects.
13b-ethyl-nor-androstenedione is about equal to testosterone in anabolic potency, yet less androgenic. This would make this compound fairly light on the hairline with minimal chance of acne or other androgenic side-effects.
With low androgenic activity, this compound may negatively affect the libido and erectile function. The lack of androgenic potency and progestational effects make this compound likely to cause gyno symptoms. Users could stack this compound with testosterone or one of its non-aromatizing metabolites to preserve DHT levels and possibly prevent these side-effects.
Users experience rapid weight gain from this compound partly due to subcutaneous water retention from the progestational activity. Therefore the overall gains from this compound may lead to a bloated appearance. Because of the progestational effects, users should avoid stacking this compound with other gyno aggravating compounds. Max LMG can aromatize to estrogen in small amounts, however not to any significant degree, therefore an aromatase inhibitor would provide little protection against this compound's side-effects.
Max LMG immediately converts in the stomach into a 13b alkylated compound (13b ethyl nor androstenedione) and then makes it all the way to the liver because it is ethylated to survive first pass, and is converted into 13b ethyl nor testosterone, a steroid similar to norbolethone aka the clear.
17b-hydroxy-2a,17b-dimethyl-5a-androstan-3-one-azine (Dymethazine)Trade Name: Dymethazine
Dymethazine (aka mebolazine) was brought to market by iForce Nutrition in 2009, however, despite Dymethazine being 'legal' it was largely taken off the market due to recent FDA activities. Despite this, clones of the original Dymethazine have already been brought to the market. Dymethazine and DZine are interchangeable featuring the same compound (2,17-dimethyl-5-androstan-17-ol-3,3-one-azine)
Dymethazine is an azine, two superdrol molecules attached to each other by a nitrogen atom. Stomach acid separates the two superdrol molecules from each other, after which they make their way to the androgen receptors. Dymethazine is also known as mebalozine.
Dymethazine is nearly identical to Superdrol, except it's two (as opposed to one) superdrol molecules attached to each other. Your body's stomach acid separates these two molecules prior to absorption, so it becomes a single molecule with two potential pathways. Despite this difference, Superdrol remains the more powerful compound.
The one advantage Dymethazine has over Superdrol is the lower likelihood/greater managability of side effects. Dymethazine is an incredibly potent compound and carries the same risks as any other powerful anabolic steroid or pro-hormone.
In a study, patients were administered Dymethazine for 45+ days. Liver values did not change for 50% of patients, while the other 50% noticed only modest to moderate increases in liver values. So, while Dymethazine can increase liver values, it is not as harsh as the current strong methyls currently available.
Dymethazine features 0% ability to aromatize and expresses an extremely weak androgenic activity. This means Dymethazine will produce gain with little to no liver impact and will cause no estrogen related side effects.
2,17a-methyl-5a-androsta-1-en-17b-ol-3-one (Methylstenbolone)An active and orally-bioavailable compound engineered to resist metabolic breakdown on both the A and D rings, precisely where other active hormonal molecules typically degrade into estrogenic or biologically-inactive metabolites.
Claims: Sperior pharmacokinetic profile and exceptional potency; does not aromatize into any estrogenic compound and has no affinity for the progesterone receptor, so estrogen and progesterone receptor mediated side effects are of no concern.
AKA methyl stenbolone, methyl sten, 17a-methyl-stenbolone, m-sten, ultradrol
In 1966, researchers at Searle Laboratories set about methodically testing the myotrophic (anabolic) and androgenic effects of a series of A-ring modified androstane derivatives. Compounds explored include
Methyl-1-testosterone (M1T), desoxymethyltestosterone (phera), 17a-methyl-1-androstenediol (Alpha One), and a variety of other 1- and 2-dehydro compounds were explored for activity.
The researchers announced that "Even the least active compound in Table 6 possessed a higher relative myotrophic potency than previously has been obtained with several clinically interesting compounds which have been studied under identical conditions, i.e. oxymetholone, oxandrolone, stanozolol, and methandrostenolone." (anadrol, anavar, winstrol, and dianabol).
Props to henryv, read the rest of his write-up at Total Flex Blog
4-chloro-17a-methyl-androst-1,4-diene-3b,17b-diol (Halodrol)Trade name: Halodrol, also known as H-Drol
Halodrol is a 17aa steroid that converts to the steroid oral Turinabol after interaction with 3b-HSD at an estimated rate of about 5%. Because of this low conversion, doses must be higher than other 17aa pro-steroids. However, it is suspected that Halodrol has decent potency without conversion as good results are seen despite the relatively low conversion to Turinabol. Halodrol appears to be about as potent as testosterone, and significantly less androgenic.
Because of the 4-chloro group, halodrol has no progestational effects, it cannot interact with the aromatase enzyme, and it produces inactive 4-chloro-DHT metabolites. This makes androgenic side-effects such as hair loss, high blood pressure, acne and prostate enlargement less likely.
The lack of androgenic potency might be expected to create problems with gyno, however the low SHBG binding affinity has minimal interference with SHBG levels and/or freely circuiting estrogen and testosterone. It does not appear that halodrol has a significant gyno risk.
Because halodrol must be used at such a high dose to see noticeable effects, liver toxicity may become an issue. Therefore it is recommended to use a liver protecting supplement before and during halodrol cycles.
Gains from Halodrol generally take a few weeks to notice, but users can expect solid increases in strength, lean muscle mass, improved vascularity and minimal water retention. This allows some of the gains to be kept after the cycle if good diet and training are continued. Quick dramatic gains in size and strength are not generally noticed with Halodrol.
H-Drol is one of the most popular and proven compounds on the market and is considered good for beginners due to it's reputation for minimal side effects and dry gains that are relatively easy to maintain after the cycle is complete.