1,4 Andro Maxx Information (Prohormones)

1,4 Andro Maxx by


Ratings
Ingredients
Manufactured by:
NRG-X Labs

Serving Size: 2 Capsules
Servings Per Container: 30

Ingredients
NRG Andro Complex 150mg
1-Androsterone, 4-Androsterone, 3,5,7-trihydroxy-4-methoxyflavon

NRG Andro BOOST Complex 150mg
ALA (Alpha Lipoic Acid), Vanadyl Sulfate, DHB

Other: Gelatin, Rice Powder, Magnesium Stearate

Bottle recommended dosage: Take one serving (2 caps) per day preferably with a meal; you can take this serving at anytime during the day however before a workout or before bed are the PRIME testosterone boosting time frames. Take for a maximum of eight weeks, then stop for at least 2-3 weeks.

I would expect anyone using this to see mild gains, mainly due to the 1-Androsterone, The 4-Andro is still fairly unproven when it comes to reliable results, at least that's what my research indicates.

The 3,5,7-trihydroxy-4-methoxyflavon is supposed to have some anti-aromatase effect, unproven in humans however. Same goes for it's supposed cholesterol leveling properties.

DHB is supposed to incite the grapefruit effect, that being more ready absorption of supplements, etc.

Current research has Vanadyl Sulfate about as useful as eating pencil eraser leavings.

ALA is a good anti-oxident. Probably even worth taking on it's own.

So overall you've got 1 mildly active compound, 1 unproven, a good anti-oxidant, something to help with supplement absorption, and some stuff that, so far, has really be shown to do much.


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1-Androstene-3b-ol,17-one (1-Androsterone)

1-Androstene-3b-ol, 17-one, (AKA 1-Androsterone and 1-DHEA) is a non-methylated pro-steroid that must convert to 1-androstenediol (1-AD), 1-androstenedione (original 1-AD) and/or 1-testosterone in order to be active.

1-Androsterone is a naturally occurring metabolite of DHEA. In the body, 1-Androsterone is converted to 1-Androstenediol and 1-Androstenedione. Both of these metabolites can then be converted to 1-Testosterone, which is where most of the effects come from. There is no conversion to estrogen.

1-Androsterone and its metabolites have relatively potent androgenic effects, therefore gyno is almost never an issue. However, because of the androgenic potency, this compound could pose a mild hair loss risk for those prone to male pattern baldness. Because this steroid is non-17aa there should be less concern about it negatively affecting the liver or cholesterol levels.

Moderate gains of lean muscle mass and strength can be expected, but users should not expect rapid increases in size or weight with this compound since extra-cellular and intra-cellular water retention are minimal. This makes the gains from this steroid fairly easy to maintain post cycle.

1-Androsterone will stack well with almost any compound. For more dramatic gains in size and strength it is recommended to stack this compound with an aromatizing steroid or possibly one of the progestational compounds listed elsewhere.

3',5,7-Trihydroxy-4'-methoxyflavanone (Hesperetin)

Generic Names: Cyanidanon 4'-Methyl Ether 1626; Hesperitin; YSO2

Hesperidin (a flavonone glycoside) is water-soluble due to the presence of the sugar part in its structure, so on ingestion it releases its aglycone, i.e, hesperetin. Hesperidin is found in Citrus fruits.

Potential uses include lowering cholesterol and, possibly, otherwise favorably affecting lipids. In vitro research also suggests the possibility that hesperetin might have some anticancer effects and that it might have some anti-aromatase activity.

4 androstene-3b-ol, 17-one

AKA
4-DHEA
4-AD

4-DHEA may appear under the nomenclature 4-androstene-3b-ol, 17-one.

4 androstene 3b-ol, 17-one is a prohormone to 4-androstenediol. And 4-androstenediol is a prohormone to testosterone.

4-DHEA does not have much anabolic activity on its own, but it converts to testosterone in a two-step process involving the enzymes 3bHSD and 17bHSD. 4-DHEA first converts to androstenediol and androstenedione and then to testosterone.

In 2004 several prohormones and steroids in food supplements were forbidden by the American government. Among them were the prohormones of testosterone. However, in the Anabolic Steroids Control Act almost no steroids with a C17 carbonyl group are mentioned. Supplement producers gratefully use this omission, and have marketed 4-androstene-3b-ol-17-one as a testosterone precursor.

Two step pro hormone. stares out as 4-dhea, must be converted to either 4-androstenedione, or 4-androstenediol, and then must convert into testosterone. Alot of chances for it to not make it to test.

It will likely convert rapidly and extensively to androstenedione. Androstenedione can convert somewhat to testosterone but it also aromatizes easily. It may (and this is quite theoretical though based on some fact) convert to testosterone better than androstenedione itself though. And that is because the first conversion can increase NADPH/NADP ratio in liver, and that will help the efficiency of the second conversion.

Eh.... seems to be a lot of conflicting info here. Do your research!

6,7-dihydroxybergamottin (DHB)

Along with the chemical Bergamottin, it is believed to be responsible for the grapefruit juice effect in which the consumption of the juice affects the metabolism of a variety of pharmaceutical drugs.

Chemically, bergamottin and 6,7-dihydroxybergamottin are linear furanocoumarins functionalized with side chains derived from geraniol. They are inhibitors of some isoforms of the cytochrome P450 enzyme, particularly CYP3A4. This prevents oxidative metabolism of certain drugs by the enzyme, resulting in an elevated concentration of drug in the bloodstream.

Normally, the grapefruit juice effect is considered to be a negative interaction, and patients are often warned not to consume grapefruit or its juice when taking medication. However, some current research is focused on the potential benefits of cytochrome P450 inhibition. Bergamottin, dihydroxybergamottin, or synthetic analogs may be developed as drugs that are targeted to increase the oral bioavailability of other drugs.

Alpha Lipoic Acid (ALA)

Alpha-lipoic acid (ALA) is an antioxidant made by the body and is found in every cell, where it helps turn glucose into energy. Unlike other antioxidants, which work only in water (such as vitamin C) or fatty tissues (such as vitamin E), ALA is both fat and water soluble.

In the cells of the body, ALA is converted into dihydrolipoic acid. ALA is not the same as alpha linolenic acid, which is an omega-3 fatty acid that may help heart health.

ALA has been proposed as a treatment for alcohol-related liver disease, but so far there is no evidence that it works. ALA has been administered by IV along with silymarin (milk thistle) to treat people who have eaten the poisonous mushroom Amanita, which causes liver damage.

Vanadyl Sulfate

Vanadyl Sulfate is the most popular and common form of vanadium, an element in the body that is found in foods such as pepper, dill, radishes, eggs, vegetable oils, buckwheat, and oats.

The physiological role of vanadium in humans is unknown, but it seems that the substance is needed for normal growth and development. Recently, a great deal of attention has been paid to vanadium because of its supposed insulin-mimicking activities. The precise mechanism by which vanadium mimics the effects of insulin is uncertain. The most popular view has been that vanadium works as a cofactor that alters the concentration and effectiveness of several enzymes that are involved in the breakdown and distribution of glucose molecules and amino acids.

The lack of research into the specific methodology and structure of vanadium has left much up to speculation. Workout supplement suppliers have taken advantage of this condition by making bold claims.

Unfortunately, vanadyl sulfate doesn't live up to its claims. The theoretical benefits of increased amounts of insulin were extrapolated from the role of insulin after a large meal. During exercise, the role of insulin in the body is diminished. Insulin is no longer the primary regulator of glucose uptake. During exercise, more glucose is made available to the muscle cell due to an increased blood flow. The rapidly moving blood transports the glucose molecules and enables the rapidly consumed supply to be replenished as needed. An increase in insulin is simply not necessary.

In addition to overestimating the potential benefits of increased insulin like activity through vanadyl sulfate, it also appears that proponents of the supplement also overlooked some of the potential dangers. Insulin does much more than enable glucose and amino acid uptake in muscle cells; it is one of the body's primary regulatory hormones. In addition, insulin also helps to synthesize both protein and fat molecules.

In December of 1996, a research team at the School of Pharmacy at the University of Otago in New Zealand performed a study on the effects of oral vanadyl sulfate on body composition and athletic performance. In the twelve week, double-blind placebo controlled test, the results were astounding. To test the strength gains of the subjects, a strength baseline was established at the beginning of the study. In addition, subjects were measured for body fat percentage and overall lean body mass. At the beginning of the study, the strength of all participants was assessed using the 1 and 10 repetition maximum for bench press and leg press. Throughout the twelve week period, subjects worked out with a partner. One subject took vanadyl sulfate (.5mg/day) and the other took a placebo. At the end of the double-blind study, the researchers concluded that with regard to side effects, oral vanadyl sulfate appeared to be well tolerated, however, they also concluded that "oral vanadyl sulfate was ineffective in changing body composition in weight -training athletes".

Specifically, both groups gained (.07%) body fat and had almost identical strength gains.