Prohormone & Supplement Ingredients:

Luteolin

Luteolin is a one of the citrus bioflavonoids and, like most flavonoids, has antioxidant, anti-inflammatory, and anti-tumor properties. Preliminary research has revealed evidence that it acts as an antioxidant, a free radical scavenger, a promoter of carbohydrate metabolism, or an immune system modulator. Basic research results indicate luteolin as an anti-inflammatory agent with other potential effects on septic shock. Luteolin is found in high amounts in parsley, thyme, peppermint, basil herb, celery and artichoke.

Luteolin exerts a variety of pharmacological activities and anti-oxidant properties associated with its capacity to scavenge oxygen and nitrogen species. It also shows potent anti-inflammatory activities by inhibiting nuclear factor kappa B (NFkB) signaling in immune cells.

University of Illinois researchers report lutelin can disrupt a component of the inflammatory response in the brain. Research found that luteolin inhibits a key pathway in the inflammatory response of microglia--brain cells key to the body's immune defense. Microglial cells exposed to luteolin show a significantly diminished inflammatory response. Luteolin reduces production of interleukin-6 in the inflammatory pathway by as much as 90 percent.
Supplements with this ingredient:
EpiFire (Prohormones)
Methyl 1-D (Test Boosters/Hormone Regulation)

Links to additional information on Luteolin
Luteolin reduces IL-6 production in microglia (Added on 1/10/2011)
Luteolin as a Therapeutic Option for Multiple Sclerosis (Added on 1/10/2011)

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