Androst-4-ene-3,11,17-trione (Adrenosterone)Know as 11-OXO, 11-Sterone, 11-Test
Nomenclature: Adrenosterone (Androst-4-ene-3,11,17-trione
Common Dosages: 300mg to 900 mg daily.
Common Cycle Length: 5-9 Weeks.
Half-Life: Average (6-8 hours)
Adrenosterone is a steroid hormone with weak androgenic effect first isolated in 1936 from the adrenal cortex. Adrenosterone occurs in trace amounts in humans as well as most mammals and in larger amounts in fish, where it is a precursor to the primary androgen, 11-ketotestosterone. Adrenosterone has shown to be converted into 11-ketotestosterone in humans, which contributes to adrenosterone's androgenic effects.
11-Keto-androstenedione or 11-keto-androstenetrione are also trade names for this hormone, while the correct name would be androst-4-ene-3,11,17-trione.
Adrenosterone's main action is it lowers cortisol levels. Cortisol is the main catabolic (muscle-eating) hormone and it also promotes fat gain. Cortisol and testosterone also work in an inverse relationship, so high cortisol levels lower testosterone. Adrenosterone acts as a competitive inhibitor, preventing cortisone from attaching to the 11b-hydroxysteroid dehydrogenase type I reductase. By competing at the receptor, it keeps cortisone from attaching and converting to cortisol through the enzyme. Andrenosterone is found naturally in the body and is released by the adrenal glands. The body uses it as a way to help regulate cortisol levels.
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Angelo Bruno (Added on 12/2/2012)
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